Je connais pas trop apache mais je tenterais un truc comme ça :
<VirtualHost *:80>
ServerAdmin xnorky@gmail.com
ServerName www.xnorky.fr
ServerAlias xxx.xxx.xxx.xxx
SuexecUserGroup rufy users
SetHandler "proxy:unix:/home/rufy/www/RuFy/run/gunicorn.sock|fcgi://127.0.0.1:8000/"
<Location /rufy>
Satisfy any
Allow from all
ProxyPass "/" "http://127.0.0.1:8000/"
ProxyPassReverse "/" "http://127.0.0.1:8000"
ProxyPreserveHost On
</Location>
Alias /rufy/static "/home/rufy/www/RuFy/static"
<Directory "/home/rufy/www/RuFy/static">
Options Indexes MultiViews FollowSymLinks
AllowOverride None
Order allow,deny
Allow from all
</Directory>
ErrorLog ${APACHE_LOG_DIR}/error_rufy.log
LogLevel warn
CustomLog ${APACHE_LOG_DIR}/access_rufy.log combined
</VirtualHost>